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OX40/TNFRSF4 Products
OX40 (CD134; TNFRSF4) is a T cell costimulatory molecule of the TNF receptor superfamily that coordinates with other costimulators (CD28, CD40, CD30, CD27 and 4-1BB) to manage the activation of the immune response. OX40 is upregulated on antigen activated CD4+ and CD8+ T cells with costimulation by CD40-CD40 Ligand and CD28-B7. OX40 interactions with OX40 Ligand on antigen presenting cells enhances T cell survival, proliferation, and cytokine production. It also inhibits the conversion of effector T cells into regulatory T cells (Tregs) and can promote the maintenance of and recall response in memory T cells. OX40 is constitutively expressed on Tregs where it promotes Treg proliferation and immunosuppressive activity. OX40-OX40 Ligand signaling is involved in allergic airway inflammation, graft-versus-host disease, and autoimmune disease.
65 results for "OX40/TNFRSF4" in Products
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OX40/TNFRSF4 Products
OX40 (CD134; TNFRSF4) is a T cell costimulatory molecule of the TNF receptor superfamily that coordinates with other costimulators (CD28, CD40, CD30, CD27 and 4-1BB) to manage the activation of the immune response. OX40 is upregulated on antigen activated CD4+ and CD8+ T cells with costimulation by CD40-CD40 Ligand and CD28-B7. OX40 interactions with OX40 Ligand on antigen presenting cells enhances T cell survival, proliferation, and cytokine production. It also inhibits the conversion of effector T cells into regulatory T cells (Tregs) and can promote the maintenance of and recall response in memory T cells. OX40 is constitutively expressed on Tregs where it promotes Treg proliferation and immunosuppressive activity. OX40-OX40 Ligand signaling is involved in allergic airway inflammation, graft-versus-host disease, and autoimmune disease.
65 results for "OX40/TNFRSF4" in Products
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunohistochemistry, Western Blot |
| Source : | NS0 |
| Accession # : | NP_003318.1 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | P47741 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #2553B |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #443318 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #977974 |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry |
| Source : | NS0 |
| Accession # : | P43489.1 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Flow Cytometry, Western Blot |
Biotinylated
| Source : | HEK293 |
| Accession # : | P43489.1 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Functional Assay, Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #443318 |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #977960 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #443318 |
| Applications : | Flow Cytometry |
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
| Source : | NS0 |
| Accession # : | P43489 |
| Applications : | Binding Activity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #977974 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #977960 |
| Applications : | Flow Cytometry |
| Source : | HEK293 |
| Accession # : | XP_005545179 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | P43489 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | XP_005545179.1 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #977960 |
| Applications : | CyTOF-ready, Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #443318 |
| Applications : | Flow Cytometry |
