Osteoadherin/OSAD: Proteins and Enzymes

Osteoadherin (OSAD), also known as Osteomodulin, is an extracellular matrix keratan sulfate proteoglycan that belongs to the class II subfamily of small leucine-rich proteoglycans (SLRP). Leucine-rich repeat (LRR) motifs consist of approximately 20 - 30 amino acids (aa) with conserved leucine spacing, folded into a structure with one beta-sheet and one alpha-helix. OSAD contains eight sulfated tyrosine residues and is distinguished from other class II SLRPs by the presence of an approximately ...