Skip to main content

109 results for "NTAL" in Products

NTAL Products

Non-T cell activation linker (NTAL), also known as linker for activation of B cells (LAB), is a transmembrane adaptor protein involved in immunoreceptor signaling. NTAL is expressed in lipid raft microdomains of B cells, mast cells, monocytes and NK cells. Rapid tyrosine phosphorylation of NTAL occurs upon BCR aggregation in B cells, Fc epsilon RI aggregation and Kit activation in mast cells, and Fc gamma RI aggregation in monocytes. Phosphorylated NTAL recruits signaling molecules such as Grb2, Gab1, and c-Cbl into receptor-signaling complexes. Defects in the NTAL gene may cause Williams-Beuren syndrome, a rare genetic disorder characterized by mild mental retardation, and abnormalities in the cardiovascular and musculo-skeletal systems.

Reactivity: Human, Mouse
Details: Mouse IgG1 Monoclonal Clone #NAP-07
Applications: WB, ICC/IF, Flow, IP, CyTOF-ready
Immunocytochemistry/ Immunofluorescence: NTAL Antibody (NAP-07) - BSA Free [NB500-341]
Applications: PAGE
SDS-PAGE: Recombinant Human NTAL His Protein [NBP1-44385]
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: WB
Western Blot: NTAL Antibody [NBP1-31177]
Applications: WB
Western Blot: NTAL Overexpression Lysate [NBL1-12446]
Applications: AC
Results Per Page
5 10 25 50
/ 5