Neuromedin BR/NMBR: Small Molecules and Peptides
NMBR (neuromedin-B receptor) is an 80 kDa, 390 amino acid (aa) G-protein coupled 7-transmembrane glycoprotein receptor for bombesin-like peptides, binding NMB with high affinity and GRP (gastrin releasing peptide) with lower affinity. NMBR expression in the olfactory and central thalamic regions of the brain plays a role in thermoregulation. It has also been shown to be mitogenic in colonic epithelium. Expression in the pituitary gland is important for the regulation of the pituitary-thyroid axis.
Products:
1 result for "Neuromedin BR/NMBR Small Molecules and Peptides" in Products
1 result for "Neuromedin BR/NMBR Small Molecules and Peptides" in Products
Neuromedin BR/NMBR: Small Molecules and Peptides
NMBR (neuromedin-B receptor) is an 80 kDa, 390 amino acid (aa) G-protein coupled 7-transmembrane glycoprotein receptor for bombesin-like peptides, binding NMB with high affinity and GRP (gastrin releasing peptide) with lower affinity. NMBR expression in the olfactory and central thalamic regions of the brain plays a role in thermoregulation. It has also been shown to be mitogenic in colonic epithelium. Expression in the pituitary gland is important for the regulation of the pituitary-thyroid axis.
Products:
GRP (BB2) and NMB (BB1) receptor antagonist
| Chemical Name: | (S)-N-[[1-(5-Methoxy-2-pyridinyl)cyclohexyl]methyl]-α-methyl-α-[[[-(4-nitrophenyl)amino]carbonyl]amino-1H-indole-3-propanamide |
| Purity: | ≥98% (HPLC) |
