3 results for "Lipoxygenase Inhibitors" in Products
Lipoxygenase Inhibitors Products
Lipoxygenases (LOXs) are a family of non-heme iron dioxygenases that are involved in the production and metabolism of fatty acid hydroperoxidases. There are six lipoxygenase isozymes; 5-LOX, 12R-LOX, 12S-LOX, 15-LOX-1 and 15-LOX-2, which catalyze the regio-selective addition of oxygen into arachidonic acid, and epidermal LOX (E-LOX) which metabolizes 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE) to a specific epoxyalcohol compound.
Different isozymes have different physiological roles; 5-, 12R...
Selective 15-lipoxygenase inhibitor
| Chemical Name: | 6,11-Dihydro[1]benzothiopyrano[4,3-b]indole |
| Purity: | ≥98% (HPLC) |
Inhibitor of 5-lipoxygenase-activating protein (FLAP)
| Alternate Names: | L-663,536 |
| Chemical Name: | 1-[(4-Chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-α,α-dimethyl-5-(1-methylethyl)-1H-Indole-2-propanoic acid |
| Purity: | ≥98% (HPLC) |
5-LOX inhibitor; orally bioavailable
| Alternate Names: | ICI D2138 |
| Chemical Name: | N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyurea |
| Purity: | ≥98% (HPLC) |
