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1 result for "LAMP-1/CD107a" in Products
LAMP-1/CD107a Products
Lysosomal associated membrane protein 1 (LAMP-1), also known as CD107a and LGP120, is an approximately 120 kDa transmembrane glycoprotein that is a major protein component of lysosomal membranes. In cytotoxic T cells and mast cells, LAMP-1 is expressed in the membranes of intracellular granules that contain effector molecules such as perforin, granzymes, eicosanoids, and histamine. LAMP-1 is presented on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets. A glycoform of LAMP-1 known as M150 is expressed on the surface of activated macrophages where it promotes T cell costimulation and a Th1 biased immune response.
Reactivity:
Human, Mouse, Primate
Details:
Mouse IgG1 Monoclonal Clone #H4A3
Applications:
IHC, WB, Flow, ICC/IF, CyTOF-ready
