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25 results for "LAG-3" in Products

LAG-3 Products

LAG-3 (Lymphocyte activation gene-3; CD223) is a transmembrane protein that binds to MHC class II molecules and negatively regulates T cell receptor signaling. It is expressed on activated T cells, NK cells, and plasmacytoid dendritic cells (pDC). LAG-3 limits the expansion of activated T cells and pDC in response to select stimuli. Proteolytic shedding of LAG-3 enables normal T cell activation by removing the negative regulation. Binding of a homodimerized soluble LAG-3/Ig fusion protein to MHC class II molecules induces maturation of immature DC as well as secretion of pro-inflammatory cytokines by cytotoxic CD8+ T cells and NK cells.

Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, Flow, CyTOF-ready
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
IHC, WB
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #1058221
Applications:
IHC, ICC/IF
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #333210
Applications:
WB

Recombinant Monoclonal Antibody.

Reactivity:
Cynomolgus Monkey
Details:
Rabbit IgG Monoclonal Clone #2561B
Applications:
Flow
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #874501
Applications:
Flow
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #1009614
Applications:
Flow
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #1009611
Applications:
Flow
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #874512
Applications:
Flow
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #874528
Applications:
Flow
Reactivity:
Mouse
Details:
Rat IgG2B Monoclonal Clone #631501
Applications:
Flow
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #874525
Applications:
WB, Flow
LAG-3 Antibody (874525) [Alexa Fluor® 350]
Reactivity:
Human, Primate
Details:
Mouse IgG1 kappa Monoclonal Clone #L4-PL33
Applications:
IHC, WB, ELISA, Flow, ICC/IF, + 1 More
LAG-3 Antibody (L4-PL33) [Alexa Fluor® 350]
Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #17B4
Applications:
IHC, WB, Flow, ICC/IF, IP, + 1 More
LAG-3 Antibody (17B4) [Alexa Fluor® 350]
Reactivity:
Human, Monkey
Details:
Mouse IgG1 Monoclonal Clone #11E3
Applications:
IHC, WB, ELISA, Flow, ICC/IF, + 1 More
LAG-3 Antibody (11E3) [Alexa Fluor® 350]
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #OTI8F6
Applications:
IHC, WB, Flow
Novus Antibodies

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Human IgG4 Monoclonal
Applications:
ELISA, Flow, Func
Novus Antibodies

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Human IgG4 Monoclonal
Applications:
ELISA, Flow, Func
Novus Antibodies

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Human IgG4 Monoclonal
Applications:
ELISA, Flow, Func
Novus Antibodies

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Human IgG4 Monoclonal
Applications:
ELISA, Flow, Func
Novus Antibodies

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Human IgG4 Monoclonal
Applications:
ELISA, Flow, Func
Novus Antibodies

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Human IgG4 Monoclonal
Applications:
ELISA, Flow, Func
Novus Antibodies
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #CL14773
Applications:
IHC
Novus Antibodies
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #CL14765
Applications:
IHC
Novus Antibodies
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