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2 results for "Lactate Dehydrogenase A/LDHA Inhibitors" in Products

Lactate Dehydrogenase A/LDHA Inhibitors Products

Lactate Dehydrogenase A (LDHA; LDH5), EC 1.1.1.27, is one of five isoforms of the lactate dehydrogenase family. It catalyzes the conversion of pyruvate to lactate under anaerobic conditions and plays a key role in the altered glycolytic metabolism that is a feature of cancer cells. LDHs are tetrameric enzymes comprising two different types of subunit, M and H; different combinations of these subunits result in five separate isoforms. LDHA, which is found mainly in skeletal muscle but also in ...

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Potent and selective LDHA inhibitor

LDHA inhibitor

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