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304 results for "Kynureninase" in Products

Kynureninase Products

Kynureninase (KYNU) catalyzes the hydrolytic cleavage of the amino acids L-kynurenine and L-3-hydroxykynurenine to give either anthranilic acid or 3-hydroxyanthranilic acid and alanine. KYNU degrades dietary tryptophan in the liver and is involved in the de novo biosynthesis of NAD+. In immune system cells, such as macrophages and microglia, KYNU catalyzes inflammatory quinolinic acid (QA) production, which may cause neuronal damage in AIDS-related dementia complex, Alzheimer's, stroke, epilepsy, and Huntington's disease.

Source: Sf 21 (baculovirus)
Accession #: NP_003928
Applications: EnzAct
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF
Western Blot: Kynureninase Antibody [NBP2-14180]
(6)
Reactivity: Human, Rat
Details: Mouse IgG2B Monoclonal Clone #OTI1H1
Applications: IHC
Immunohistochemistry: Kynureninase Antibody (OTI1H1) - Azide and BSA Free [NBP2-71400]
(9)
Reactivity: Human, Rat
Details: Mouse IgG2B Monoclonal Clone #OTI1H1
Applications: IHC
Immunohistochemistry-Paraffin: Kynureninase Antibody (OTI1H1) [NBP2-45579]
(9)
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