IL-17B: Proteins and Enzymes

Interleukin-17B is an approximately 20 kDa glycosylated cytokine that plays a role in inflammation and bone growth. IL-17B binds to IL-17 RB and induces the production of inflammatory cytokines and the infiltration of inflammatory immune cells. It is expressed in the central nervous system, testis, ovary, stomach, pancreas, and small intestine. In the skeletal system, IL-17B is expressed in bone collars surrounding primary ossification centers as well as in epiphyseal plate chondrocytes during ...