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7 results for "Histone Deacetylase Inhibitors" in Products

Histone Deacetylase Inhibitors Products

There are 18 Histone deacetylases (HDAC) enzymes that are classified in to two families, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided in to class I (HDACs 1/2/3 and 8), class II (HDACs 4/5/6/7/9/10) and class IV (HDAC 11). The sirtuin family are all classified as class III HDACs. HDACs catalyze acetyl group removal from lysine residues in histones and non-histone proteins, causing transcriptional repression. In general, they do not act ...

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Pan-histone deacetylase inhibitor

Chemical Name: (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide
Purity: ≥98% (HPLC)
Pan-histone deacetylase inhibitor

PARP-1 inhibitor

Chemical Name: Pyridine-3-carboxamide
Purity: ≥99% (HPLC)
iPSC-derived Human Intestinal Organoid
(5)

Potent and selective class IIa HDAC inhibitor; brain penetrant

Chemical Name: 2-(2-Fluorophenyl)-N-hydroxy-2-(4-(5-(trifluoromethyl)pyrimidin-2-yl)phenyl)acetamide
Purity: ≥98% (HPLC)
Potent and selective class IIa HDAC inhibitor; brain penetrant

Pan Jumonji inhibitor; active in vivo

Chemical Name: 5-Chloro-2-[(E)-2-[phenyl(pyridin-2-yl)methylidene]hydrazin-1-yl]pyridine
Purity: ≥98% (HPLC)
Pan Jumonji inhibitor; active in vivo

Highly potent and selective HDAC2 inhibitor

Chemical Name: Ethyl N-[4-oxo-4-[(2-phenylethyl)amino]butyl]carbamate
Purity: ≥98% (HPLC)
Highly potent and selective HDAC2 inhibitor

Selective HDAC11 inhibitor

Chemical Name: N'-Hexadecylthiophene-2-carbohydrazide
Purity: ≥95% (HPLC)
Selective HDAC11 inhibitor

Potent pan-HDAC inhibitor

Chemical Name: (2E)-N-Hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide
Purity: ≥98% (HPLC)
Potent pan-HDAC inhibitor
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