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21 results for "histone-acetyltransferase-inhibitors&view=expanded" in Products

Negative control for iP300w (Cat. No. 7270)

Chemical Name:
(1'R,3'S)-3'-Fluoro-N-[(4-fluorophenyl)methyl]-2',3'-dihydro-5'-[1-[2-(methylamino)-2-oxoethyl]-1H-pyrazol-4-yl]-2,5-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[imidazolidine-4,1'-[1H]indene]-1-acetamide
Purity:
≥98%
Negative control for iP300w (Cat. No. 7270)

Inhibitor of KAT5 (Tip60)

Chemical Name:
5-(1,2-Thiazol-5-yldisulfanyl)-1,2-thiazole
Inhibitor of KAT5 (Tip60)

Potent and selective p300/CBP inhibitor; orally bioavailable

Chemical Name:
(1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2',4'-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5'-oxazolidine]-3'-acetamide
Purity:
≥98%
Potent and selective p300/CBP inhibitor; orally bioavailable

Selective EP300 Degrader (PROTAC®)

Chemical Name:
(2S,4R)-1-((S)-2-(8-(2-(4-(6-((R)-2-(((S)-2-(4-Cyanophenyl)propyl)amino)-2-phenylacetamido)pyridin-3-yl)-1H-pyrazol-1-yl)acetamido)octanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide
Purity:
≥95%
Selective EP300 Degrader (PROTAC®)

Potent p300/CBP inhibitor

Chemical Name:
(1'S,3'R)-3'-Fluoro-N-[(4-fluorophenyl)methyl]-2',3'-dihydro-5'-[1-[2-(methylamino)-2-oxoethyl]-1H-pyrazol-4-yl]-2,5-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[imidazolidine-4,1'-[1H]indene]-1-acetamide
Purity:
≥98%
Potent p300/CBP inhibitor

Reversible and non-competitive CBP/p300 inhibitor

Chemical Name:
5-[(4-Hydroxy-2,6-dimethylphenyl)methylene]-1,3-bis(phenylmethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
Purity:
≥98%
Reversible and non-competitive CBP/p300 inhibitor

High affinity KAT6A (MOZ) competitive inhibitor

Chemical Name:
2-Fluoro-N'-(3-fluoro-5-(pyridin-2-yl)benzoyl)benzenesulfonohydrazide
Purity:
≥98%
High affinity KAT6A (MOZ) competitive inhibitor

Potent and selective KAT6A and KAT6B inhibitor

Chemical Name:
N'-(4-Fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)benzenesulfonohydrazide
Purity:
≥98%
Potent and selective KAT6A and KAT6B inhibitor

Lysine acetyltransferase HBO1 (KAT7) inhibitor

Chemical Name:
N'-(4-Fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)-3-hydroxybenzenesulfonohydrazide
Purity:
≥98%
Lysine acetyltransferase HBO1 (KAT7) inhibitor

Potent and selective EP300 Degrader (PROTAC®)

Chemical Name:
12-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)-N-((R)-3'-(2-((4-fluorobenzyl)((S)-1,1,1-trifluoropropan-2-yl)amino)-2-oxoethyl)-2',4'-dioxo-2,3-dihydrospiro[indene-1,5'-oxazolidin]-5-yl)dodecanamide
Purity:
≥98%
Potent and selective EP300 Degrader
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