GRAP2 Products
GRAP2 (GRB2 related adaptor protein 2), a divergent member of the GRB2/Sem5/Drk family, is an adaptor protein involved in leukocyte-specific protein-tyrosine kinase signaing. GRAP2 shares similar structural organization as GRB2 and GRAP with a central SH2 domain flanked by two SH3 domains. However, unlike GRB2 and GRAP, the SH2 domain and the C-terminal SH3 domain of GRAP2 contains a unique 120-amino acid glutamine/proline rich sequence. In T lymphocytes, GRAP2 interacts with LAT and SLP-76 to regulate NF-AT (nuclear factor of activated T cells) and form a signaling complex with HPK1 to mediate the JNK signaling pathway. GRAP2 also interacts with M-CSF R and the activated T cell co-stimulatory receptor CD28.
104 results for "GRAP2" in Products
104 results for "GRAP2" in Products
GRAP2 Products
GRAP2 (GRB2 related adaptor protein 2), a divergent member of the GRB2/Sem5/Drk family, is an adaptor protein involved in leukocyte-specific protein-tyrosine kinase signaing. GRAP2 shares similar structural organization as GRB2 and GRAP with a central SH2 domain flanked by two SH3 domains. However, unlike GRB2 and GRAP, the SH2 domain and the C-terminal SH3 domain of GRAP2 contains a unique 120-amino acid glutamine/proline rich sequence. In T lymphocytes, GRAP2 interacts with LAT and SLP-76 to regulate NF-AT (nuclear factor of activated T cells) and form a signaling complex with HPK1 to mediate the JNK signaling pathway. GRAP2 also interacts with M-CSF R and the activated T cell co-stimulatory receptor CD28.
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
| Applications: | IHC, WB, Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1G2 |
| Applications: | IHC, WB, Flow, CyTOF-ready |
![Western Blot: GRAP2 Antibody (OTI1G2)Azide and BSA Free [NBP2-71457]](https://resources.bio-techne.com/images/products/GRAP2-Antibody-OTI1G2-Azide-and-BSA-Free-Western-Blot-NBP2-71457-img0002.jpg "Western Blot: GRAP2 Antibody (OTI1G2)Azide and BSA Free [NBP2-71457]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #475804 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #475804 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #1G12 |
| Applications: | IHC, WB, ELISA, IP |
![Western Blot: GRAP2 Antibody (1G12) [H00009402-M01]](https://resources.bio-techne.com/images/products/GRAP2-Antibody-1G12-Western-Blot-H00009402-M01-img0009.jpg "Western Blot: GRAP2 Antibody (1G12) [H00009402-M01]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #475804 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #475804 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #475804 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #475804 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #475804 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #475804 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #475804 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: GRAP2 Antibody [NBP1-83399]](https://resources.bio-techne.com/images/products/GRAP2-Antibody-Immunohistochemistry-Paraffin-NBP1-83399-img0010.jpg "Immunohistochemistry-Paraffin: GRAP2 Antibody [NBP1-83399]")
![Western Blot: GRAP2 Overexpression Lysate [NBL1-11324]](https://resources.bio-techne.com/images/products/GRAP2-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11324-img0002.jpg "Western Blot: GRAP2 Overexpression Lysate [NBL1-11324]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: GRAP2 Antibody [NB100-805]](https://resources.bio-techne.com/images/products/GRAP2-Antibody-Western-Blot-NB100-805-img0006.jpg "Western Blot: GRAP2 Antibody [NB100-805]")
| Applications: | PAGE |
