Glypican 4 Products
Glypican 4, also known as K-Glypican, is an approximately 220 kDa GPI-anchored heparan sulfate proteoglycan with a 60 kDa protein core. It is expressed in the brain, kidney, adrenal gland, and fat tissue and binds to FGF basic. In the developing brain, Glypican 4 is found in lateral ventricles surrounding the telencephalon, the dentate gyrus, proliferating neuroepithelial cells, and neural precursors. It inhibits the dopaminergic differentiation of neurons.
A 30 kDa cleaved form of Glypican 4 binds in cis to PTP sigma and contributes to excitatory synapse development and function. Glypican 4 is differentially expressed between adipose tissue depots. A soluble form can be released by adipocytes and circulates at elevated levels in obese patients with insulin resistance. This form binds and enhances signaling through the Insulin R, and it also supports adipocyte differentiation.
Products:
117 results for "Glypican 4" in Products
117 results for "Glypican 4" in Products
Glypican 4 Products
Glypican 4, also known as K-Glypican, is an approximately 220 kDa GPI-anchored heparan sulfate proteoglycan with a 60 kDa protein core. It is expressed in the brain, kidney, adrenal gland, and fat tissue and binds to FGF basic. In the developing brain, Glypican 4 is found in lateral ventricles surrounding the telencephalon, the dentate gyrus, proliferating neuroepithelial cells, and neural precursors. It inhibits the dopaminergic differentiation of neurons.
A 30 kDa cleaved form of Glypican 4 binds in cis to PTP sigma and contributes to excitatory synapse development and function. Glypican 4 is differentially expressed between adipose tissue depots. A soluble form can be released by adipocytes and circulates at elevated levels in obese patients with insulin resistance. This form binds and enhances signaling through the Insulin R, and it also supports adipocyte differentiation.
Products:
| Source: | CHO |
| Accession #: | O75487 |
| Applications: | BA |
| Assay Range: | 156 - 10,000 pg/mL |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Glypican 4 Antibody [NBP1-87697]](https://resources.bio-techne.com/images/products/Glypican-4-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-87697-img0005.jpg "Immunocytochemistry/ Immunofluorescence: Glypican 4 Antibody [NBP1-87697]")
| Reactivity: | Human, Mouse, Rat, Hamster, Bat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Glypican 4 Antibody - BSA Free [NBP1-39605]](https://resources.bio-techne.com/images/products/Glypican-4-Antibody---BSA-Free-Immunohistochemistry-Paraffin-NBP1-39605-img0002.jpg "Immunohistochemistry-Paraffin: Glypican 4 Antibody - BSA Free [NBP1-39605]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #51E3 |
| Applications: | WB, ELISA, ICC/IF, Flow |
![Western Blot: Glypican 4 Antibody (51E3)BSA Free [NBP2-49892]](https://resources.bio-techne.com/images/products/Glypican-4-Antibody-51E3-Western-Blot-NBP2-49892-img0008.jpg "Western Blot: Glypican 4 Antibody (51E3)BSA Free [NBP2-49892]")
| Applications: | ELISA |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Glypican 4 Antibody [NBP3-17858]](https://resources.bio-techne.com/images/products/Glypican-4-Antibody-Immunocytochemistry-Immunofluorescence-NBP3-17858-img0002.jpg "Immunocytochemistry/ Immunofluorescence: Glypican 4 Antibody [NBP3-17858]")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #965523 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Glypican 4 Antibody [NBP3-14338]](https://resources.bio-techne.com/images/products/Glypican "Immunohistochemistry-Paraffin: Glypican 4 Antibody [NBP3-14338]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #961609 |
| Applications: | ELISA, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #965523 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #961609 |
| Applications: | ELISA, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #961609 |
| Applications: | ELISA, Flow, CyTOF-ready |
![Glypican 4 Antibody (961609) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/fab9195cl1_mouse-glypican-4-mab-961609-corafluor-1-269202517135910.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #51E3 |
| Applications: | WB, ELISA, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #51E3 |
| Applications: | WB, ELISA, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #51E3 |
| Applications: | WB, ELISA, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #51E3 |
| Applications: | WB, ELISA, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #51E3 |
| Applications: | WB, ELISA, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #51E3 |
| Applications: | WB, ELISA, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #51E3 |
| Applications: | WB, ELISA, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #965523 |
| Applications: | ELISA |