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5 results for "Gelsolin/GSN ELISA Kits" in Products
Gelsolin/GSN ELISA Kits
Gelsolin is a calcium regulated actin binding protein. Gelsolin is a regulator of actin filament assembly and disassembly and consists of six homologous subdomains (S1-S6). When C-terminal tail (S6) is bound to calcium ion, it straightens and exposes actin binding sites located on S2s helices, leading to Gelsolin actin-serving activity (1). Gelsolin is inhibited by phosphatidylinositol (4,5)-bisphosphate (PIP2), where PIP2 will bind to S1, S2, and S3 sites. Gelsolin is involved in podosome formation and has been linked to inhibition of apoptosis by preventing release of cytochrome C (2).
Reactivity:
Human
Assay Range:
6.25 - 400 ng/mL
Applications:
ELISA
Reactivity:
Human
Assay Range:
6.25 - 400 ng/mL
Applications:
ELISA
Reactivity:
Rat
Assay Range:
15.63 - 1000 ng/mL
Applications:
ELISA
Reactivity:
Mouse
Assay Range:
78.1 - 5000 ng/mL (example only; lot dependent)
Applications:
ELISA
Reactivity:
Mouse
Assay Range:
78.1 - 5000 ng/mL (example only; lot dependent)
Applications:
ELISA