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Galectin-7 Products

The galectins constitute a large family of carbohydrate-binding proteins with specificity for N-acetyl-lactosamine-containing glycoproteins. Galectin-7 is a prototype monomeric galectin and is specifically expressed in stratified epithelia, notably in epidermis, but is barely detectable in epidermal tumors and significantly down regulated or absent from squamous carconima cell lines. The Galectin-7 gene is induced by tumor suppressor protein p53 transcriptional activity following genotoxic events. Galectin-7 is a proapoptitic protein that functions intracellularly upstream of JNK activation and Cytochrome-c release. It has been shown to increase the susceptibility of keratinocytes to UVB induced apoptosis, an essential processss in the maintenance of epidermal homeostasis.

 

18 results for "Galectin-7" in Products

Galectin-7 Products

The galectins constitute a large family of carbohydrate-binding proteins with specificity for N-acetyl-lactosamine-containing glycoproteins. Galectin-7 is a prototype monomeric galectin and is specifically expressed in stratified epithelia, notably in epidermis, but is barely detectable in epidermal tumors and significantly down regulated or absent from squamous carconima cell lines. The Galectin-7 gene is induced by tumor suppressor protein p53 transcriptional activity following genotoxic events. Galectin-7 is a proapoptitic protein that functions intracellularly upstream of JNK activation and Cytochrome-c release. It has been shown to increase the susceptibility of keratinocytes to UVB induced apoptosis, an essential processss in the maintenance of epidermal homeostasis.

 

18 results for "Galectin-7" in Products

ELISA
ELISA
WB, IHC
WB, IHC
WB, Simple Western, IHC
BA
WB, Flow, IHC, CyTOF-ready, ICC
Catalog #: FAB13392G
Flow
WB, IHC, ICC
Catalog #: BAF1304
WB
Catalog #: BAF1339
WB, IHC
Catalog #: FAB13392R
Flow
Catalog #: FAB13392V
Flow
Catalog #: FAB13392S
Flow
Catalog #: FAB13392T
Flow
Catalog #: FAB13392U
Flow
Catalog #: FAB13392N
Flow
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