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Frizzled-10 Products

This group of G protein-coupled receptors consists of 10 structurally-related, seven transmembrane proteins with a divergent N-terminal signal peptide and a variable-length C-terminal tail. The Frizzled family proteins contain a highly conserved cysteine-rich domain and a variable length linker region. Frizzled proteins function as receptors for Wnt proteins and can activate canonical Wnt/beta-catenin signaling as well as non-canonical pathways (Planar Cell Polarity and Wnt/Ca2+ Pathways). Wnt/Frizzled signaling is involved in a variety of developmental processes including cell fate determination, cell polarity, tissue patterning, and control of cell proliferation. Activation of a given Wnt/Frizzled signaling cascade is dependent on the Wnt ligand and the cell context. Frizzled proteins also form co-receptor complexes with LRP, ROR, and Ryk molecules.

21 results for "Frizzled-10" in Products

Frizzled-10 Products

This group of G protein-coupled receptors consists of 10 structurally-related, seven transmembrane proteins with a divergent N-terminal signal peptide and a variable-length C-terminal tail. The Frizzled family proteins contain a highly conserved cysteine-rich domain and a variable length linker region. Frizzled proteins function as receptors for Wnt proteins and can activate canonical Wnt/beta-catenin signaling as well as non-canonical pathways (Planar Cell Polarity and Wnt/Ca2+ Pathways). Wnt/Frizzled signaling is involved in a variety of developmental processes including cell fate determination, cell polarity, tissue patterning, and control of cell proliferation. Activation of a given Wnt/Frizzled signaling cascade is dependent on the Wnt ligand and the cell context. Frizzled proteins also form co-receptor complexes with LRP, ROR, and Ryk molecules.

21 results for "Frizzled-10" in Products

IHC, ICFlow

Recombinant Monoclonal Antibody.

IHC
BA
Catalog #: FAB34581V
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB34581S
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB34581N
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB34581R
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB34581G
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB34581T
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB34581U
Flow

Recombinant Monoclonal Antibody.

Catalog #: RDC0126
Catalog #: RDC0127
IHC, WB
ICC/IF, IHC
ICC/IF, IHC
Catalog #: NBP1-85754PEP
AC
Catalog #: NBP1-85753PEP
AC
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