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FGFR1 alpha Products
FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGFR1 through 5. FGFRs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGFR1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGFR5 does not. Multiple forms of FGFR1, 2, and 3 are generated by alternative splicing.
15 results for "FGFR1 alpha" in Products
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FGFR1 alpha Products
FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGFR1 through 5. FGFRs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGFR1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGFR5 does not. Multiple forms of FGFR1, 2, and 3 are generated by alternative splicing.
15 results for "FGFR1 alpha" in Products
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1058809 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Western Blot |
PDGFR, VEGFR and FGFR inhibitor
| Alternate Names : | TSU68, Orantinib |
| Chemical Name : | 5-[1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid |
| Purity : | ≥99% (HPLC) |
Biotinylated
| Source : | CHO |
| Accession # : | NP_075598.2 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | NP_056934 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | NP_056934 |
| Applications : | Bioactivity |
| Source : | HEK293 |
| Accession # : | P11362.3 |
| Applications : | Bioactivity |
Potent, irreversible FGFR inhibitor
| Chemical Name : | N-(3-((3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-(4-(diethylamino)butylamino)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)methyl)phenyl)acrylamide |
| Purity : | ≥96% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1058809 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1058809 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1058809 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1058809 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1058809 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1058809 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1058809 |
| Applications : | Flow Cytometry |
