Skip to main content

Fc gamma RIIIA/CD16a Products

Fc gamma RIIIA/CD16a is a low/intermediate affinity activating receptor for polyvalent immune-complexed IgG. It is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody-dependent cytotoxicity, and clearance of immune complexes. It is expressed on NK cells, T cells, monocytes, and macrophages. It is closely related to the GPI-linked Fc gamma RIIIB which is expressed on neutrophils and eosinophils. Surface expression requires interaction with an accessory chain, either the common gamma-chain or CD3 zeta. Shed forms of both Fc gamma RIIIA and Fc gamma RIIIB can be generated by proteolytic cleavage and retain binding activity. Soluble Fc gamma RIII circulates in normal plasma and is elevated in rheumatoid arthritis and in coronary artery diseases.

 

49 results for "Fc gamma RIIIA/CD16a" in Products

Fc gamma RIIIA/CD16a Products

Fc gamma RIIIA/CD16a is a low/intermediate affinity activating receptor for polyvalent immune-complexed IgG. It is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody-dependent cytotoxicity, and clearance of immune complexes. It is expressed on NK cells, T cells, monocytes, and macrophages. It is closely related to the GPI-linked Fc gamma RIIIB which is expressed on neutrophils and eosinophils. Surface expression requires interaction with an accessory chain, either the common gamma-chain or CD3 zeta. Shed forms of both Fc gamma RIIIA and Fc gamma RIIIB can be generated by proteolytic cleavage and retain binding activity. Soluble Fc gamma RIII circulates in normal plasma and is elevated in rheumatoid arthritis and in coronary artery diseases.

 

49 results for "Fc gamma RIIIA/CD16a" in Products

BA

Biotinylated

Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies

Isoform V176, His-tag

WB, Flow, IHC, CyTOF-ready, ICC
WB, Block
BA

Biotinylated Isoform V176

Catalog #: FAB2546T
Flow
Flow, CyTOF-ready
Catalog #: BAF1597
WB
BA

Low-affinity V176F polymorphic variant

Catalog #: FAB2546G
Flow
Catalog #: FAB4325G
Flow
Flow, IHC, CyTOF-ready, ICC
Catalog #: FAB2546S
Flow
Flow
Catalog #: FAB2546R
Flow
Catalog #: FAB43251G
Flow
Catalog #: FAB43251T
Flow
Catalog #: FAB2546V
Flow
Flow, IHC, ICC
Catalog #: FAB4325U
Flow
/ 2
Results Per Page
5 10 25 50