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EPCR Products
EPCR (the Endothelial Protein C Receptor), also known as CD201, is a transmembrane glyoprotein expressed on vascular endothelial cells. EPCR inhibits thrombosis through its interactions with Protein C, activated Protein C (APC), and Coagulation Factors VII, and VIIa. It enhances the activation of Protein C in response to complexes of Thrombin-Thrombomodulin. A soluble form of EPCR inhibits the anti-coagulant activity of APC. EPCR binds to CD11b/CD18 (Mac-1) on monocytes and mediates monocyte adhesion to the vascular endothelium. In addition, it binds to the antigen receptor on gamma/delta T cells, promotes hematopoietic stem cell retention in the bone marrow, and contributes to malaria pathogenicity through binding surface proteins on Plasmodium.
19 results for "EPCR" in Products
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EPCR Products
EPCR (the Endothelial Protein C Receptor), also known as CD201, is a transmembrane glyoprotein expressed on vascular endothelial cells. EPCR inhibits thrombosis through its interactions with Protein C, activated Protein C (APC), and Coagulation Factors VII, and VIIa. It enhances the activation of Protein C in response to complexes of Thrombin-Thrombomodulin. A soluble form of EPCR inhibits the anti-coagulant activity of APC. EPCR binds to CD11b/CD18 (Mac-1) on monocytes and mediates monocyte adhesion to the vascular endothelium. In addition, it binds to the antigen receptor on gamma/delta T cells, promotes hematopoietic stem cell retention in the bone marrow, and contributes to malaria pathogenicity through binding surface proteins on Plasmodium.
19 results for "EPCR" in Products
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Immunohistochemistry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Flow Cytometry, Immunohistochemistry, Western Blot |
| Assay Range : | 0.312 - 20 ng/mL |
| Applications : | ELISA |
| Source : | NS0 |
| Accession # : | Q9UNN8 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #304519 |
| Applications : | Immunohistochemistry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Flow Cytometry, Immunocytochemistry/Immunofluorescence, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #304511 |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #432714 |
| Applications : | CyTOF-ready, Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #432732 |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #432714 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #432714 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #432714 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #432714 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #432714 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #432714 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #432714 |
| Applications : | Flow Cytometry |
| Source : | NS0 |
| Accession # : | AAC42049 |
| Applications : | Bioactivity |
