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Endothelin ETB Receptor Antagonists Products
EDNRA and EDNRB (endothelin A and B receptors, respectively) are members of the rhodopsin-like 7-transmembrane receptor family. EDNRA binds endothelins ET-1 and ET-2 preferentially, and is expressed on vascular smooth muscle where it mediates vasoconstriction. EDNRB binds all three endothelin forms equally, and is expressed on endothelial cells where it mediates vasodilation.
2 results for "Endothelin ETB Receptor Antagonists" in Products
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Endothelin ETB Receptor Antagonists Products
EDNRA and EDNRB (endothelin A and B receptors, respectively) are members of the rhodopsin-like 7-transmembrane receptor family. EDNRA binds endothelins ET-1 and ET-2 preferentially, and is expressed on vascular smooth muscle where it mediates vasoconstriction. EDNRB binds all three endothelin forms equally, and is expressed on endothelial cells where it mediates vasodilation.
2 results for "Endothelin ETB Receptor Antagonists" in Products
Selective ETB antagonist
| Chemical Name : | N-[(cis-2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine sodium salt |
| Purity : | ≥95% (HPLC) |
Potent ETB antagonist
| Chemical Name : | N-3-[1,1'-Biphenyl]-4-yl-N-(3,5-dimethylbenzoyl)-N-methyl-D-alanyl-L-tryptophan |
| Purity : | ≥99% (HPLC) |
