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4 results for "Endothelin-1" in Products

Endothelin-1 Products

Endothelin-1 (ET-1) is a vascular endothelium derived peptide that acts as a potent vasoconstrictor. It is processed by a furin-like protease to yield a peptide termed Big ET-1. Big ET-1 is then cleaved by ECE-1, producing the mature form ET-1 (1-21). ET-1 expression is induced by mechanical stimulation, various hormones, and pro-inflammatory cytokines. Its production is inhibited by nitric oxide, prostacyclin, and atrial natriuretic peptide (ANP). ET-1 exerts its vasoconstrictor effects ...

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Reactivity:
Human, Mouse, Rat, Porcine, Canine, +2 More
Details:
Mouse IgG1 Monoclonal Clone #TR.ET.48.5
Applications:
IHC, WB, Flow, ICC/IF, Func
Endothelin-1 Antibody (TR.ET.48.5) [mFluor Violet 610 SE]
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