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2 results for "Dkk-1" in Products
Dkk-1 Products
Dkk-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling. It interacts with LRP-6, and internalized complexes of Dkk-1/LRP-6/Kremen 2 can downregulate Wnt signaling. The balance between Wnt signaling and Dkk-1 inhibition is critical for bone formation and homeostasis. In addition, Dkk-1 can act as either a tumor suppressor or promoter of metastasis.
Reactivity:
Rat
Assay Range:
0.31 - 20 ng/mL
Applications:
ELISA
Reactivity:
Porcine
Assay Range:
31.25 - 2000 pg/mL
Applications:
ELISA
