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5 results for "DEK Antibodies" in Products
DEK Antibodies
The DEK oncogene is an approximately 45 kDa phosphoprotein with pleiotropic activities. It is a chromatin remodeling factor, a transcriptional coactivator and corepressor, a component of RNA spliceosomes, and a promoter of DNA repair during apoptosis. DEK is upregulated in many cancers and promotes epithelial cell transformation. It functions as a proinflammatory factor when secreted by activated macrophages. It is an autoantigen in juvenile arthritis and lupus and a target of chromosomal translocation with the CAN gene in acute myelogenous leukemia. DEK contains one SAP domain (aa 149-183), one nuclear localization sequence (aa 205-221), and a DNA-binding C-terminal domain (aa 321-375).
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #715524
Applications:
IHC, WB
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #715511
Applications:
IHC, ICC/IF
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
IHC, IP, WB (-)
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
WB, ICC/IF, IP
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
ICC/IF