1 result for "DCLK1 Small Molecules and Peptides" in Products
DCLK1: Small Molecules and Peptides
Doublecortin-like and CAM Kinase-like 1 (DCLK1), also known as DCAMKL1, is a member of the CaMK subfamily of Ser/Thr protein kinases. Human DCLK1 is 740 amino acids (aa) in length with a predicted molecular weight of approximately 82 kDa. It shares 96% aa sequence identity with the mouse ortholog. DCLK1 contains two doublecortin domains, located at aa 57-143 and 186-269, and a protein kinase domain at aa 390-647. Alternative splicing produces multiple isoforms including, DCL, which contains an ...
Potent and selective doublecortin like kinase 1/2 (DCLK1/2) inhibitor; orally bioavailable
| Chemical Name: | 5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-5-(2,2,2-trifluoroethyl)-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
| Purity: | ≥98% (HPLC) |
