Cysteinyl Leukotriene R1/CysLTR1: Proteins and Enzymes
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, CysLTR1 and CysLTR2. Both receptors are members of the superfamily of G protein-coupled receptors. Activation of CysLTR1 by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
1 result for "Cysteinyl Leukotriene R1/CysLTR1 Proteins and Enzymes" in Products
1 result for "Cysteinyl Leukotriene R1/CysLTR1 Proteins and Enzymes" in Products
Cysteinyl Leukotriene R1/CysLTR1: Proteins and Enzymes
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, CysLTR1 and CysLTR2. Both receptors are members of the superfamily of G protein-coupled receptors. Activation of CysLTR1 by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
| Applications: | AC |