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3 results for "Complement Factor B" in Products

Complement Factor B Products

Complement factor B is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease that associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits ...

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Reactivity:
Human
Assay Range:
2.188 - 140 ng/mL (example only; lot dependent)
Applications:
ELISA
ELISA: Human Complement Factor B ELISA Kit (Colorimetric) [NBP2-60564]
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