50 results for "CIP2A" in Products
CIP2A Products
Inhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for the transformation of human cells. The protein, designated Cancerous Inhibitor of PP2A (CIP2A), interacts directly with the oncogenic transcription factor c-Myc, inhibits PP2A activity toward c-Myc serine 62 (S62), and thereby prevents c-Myc proteolytic degradation. In addition to its function in c-Myc stabilization, CIP2A promotes anchorage-independent cell growth and in vivo tumor formation. The oncogenic activity of CIP2A is demonstrated by transformation of human cells by overexpression of CIP2A. Importantly, CIP2A is overexpressed in two common human malignancies, head and neck squamous cell carcinoma (HNSCC) and colon cancer.
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
![Knockdown Validated: CIP2A Antibody (2G10) [NB110-59722]](https://resources.bio-techne.com/images/products/CIP2A-Antibody-2G10-Knockdown-Validated-NB110-59722-img0013.jpg "Western Blot: CIP2A Antibody (2G10) [NB110-59722]")
CIP2A Antibody (24GB8025)
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #24GB8025 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Flow, MS |
![Western Blot: CIP2A Antibody [NB100-74663]](https://resources.bio-techne.com/images/products/CIP2A-Antibody-Western-Blot-NB100-74663-img0011.jpg "Western Blot: CIP2A Antibody [NB100-74663]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP, Mycoplasma |
![Western Blot: CIP2A Antibody [NB100-68264]](https://resources.bio-techne.com/images/products/CIP2A-Antibody-Western-Blot-NB100-68264-img0005.jpg "Western Blot: CIP2A Antibody [NB100-68264]")
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
![Western Blot: CIP2A Antibody (2G10)Azide and BSA Free [NBP2-80670]](https://resources.bio-techne.com/images/products/CIP2A-Antibody-2G10-Azide-and-BSA-Free-Western-Blot-NBP2-80670-img0002.jpg "Western Blot: CIP2A Antibody (2G10)Azide and BSA Free [NBP2-80670]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: CIP2A Antibody [NBP2-48710]](https://resources.bio-techne.com/images/products/CIP2A-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-48710-img0001.jpg "Immunocytochemistry/ Immunofluorescence: CIP2A Antibody [NBP2-48710]")
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
![Western Blot: CIP2A Overexpression Lysate [NBL1-12266]](https://resources.bio-techne.com/images/products/CIP2A-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12266-img0002.jpg "Western Blot: CIP2A Overexpression Lysate [NBL1-12266]")
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
![CIP2A Antibody (2G10) [mFluor Violet 500 SE]](https://resources.bio-techne.com/images/products/nb110-59722mfv500_mouse-cip2a-mab-2g10-mfluor-violet-500-se-57202313114248.png "CIP2A Antibody (2G10) [mFluor Violet 500 SE] -")
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
![CIP2A Antibody (2G10) [mFluor Violet 610 SE]](https://resources.bio-techne.com/images/products/nb110-59722mfv610_mouse-cip2a-mab-2g10-mfluor-violet-610-se-57202315332124.png "CIP2A Antibody (2G10) [mFluor Violet 610 SE] [NB110-59722MFV610] -")
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2G10 |
| Applications: | IHC, WB, ICC/IF, Flow, Mycoplasma |