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Chordin-like 2/CHRDL2 Products

Chordin-like 2 (CHL2, CHRDL2, or BNF-1), is a secreted glycoprotein that functions as a BMP antagonist. It is expressed in chondrocytes in developing joint cartilage, osteoblasts, myotubes, brain, some carcinomas, and the genitourinary system (e.g. uterus, prostate, testis, bladder). CHL2 binds to multiple TGF-beta superfamily proteins including BMP-2, -4, -5, -6, -7, GDF-5, Activin A, and TSG. It prevents the binding of BMPs to type 1 and type 2 receptors as well as BMP-induced cellular responses. CHL2 reduces the rate of matrix deposition by mesenchymal cells, acting as a negative regulator of cartilage formation.

16 results for "Chordin-like 2/CHRDL2" in Products

Chordin-like 2/CHRDL2 Products

Chordin-like 2 (CHL2, CHRDL2, or BNF-1), is a secreted glycoprotein that functions as a BMP antagonist. It is expressed in chondrocytes in developing joint cartilage, osteoblasts, myotubes, brain, some carcinomas, and the genitourinary system (e.g. uterus, prostate, testis, bladder). CHL2 binds to multiple TGF-beta superfamily proteins including BMP-2, -4, -5, -6, -7, GDF-5, Activin A, and TSG. It prevents the binding of BMPs to type 1 and type 2 receptors as well as BMP-induced cellular responses. CHL2 reduces the rate of matrix deposition by mesenchymal cells, acting as a negative regulator of cartilage formation.

16 results for "Chordin-like 2/CHRDL2" in Products

Catalog #: MAB24481
WB, ICFlow
Catalog #: 2520-CH
BA
Catalog #: 9127-CH
BA
WB, IHC
WB, IHC, IP
Catalog #: MAB2448
WB, IP
Catalog #: BAF2520
WB
Catalog #: BAF2448
WB, IHC
Catalog #: AF2520
WB
Catalog #: IC24481S
ICFlow
Catalog #: IC24481R
ICFlow
Catalog #: IC24481N
ICFlow
Catalog #: IC24481V
ICFlow
Catalog #: IC24481T
ICFlow
Catalog #: IC24481G
ICFlow
Catalog #: IC24481U
ICFlow
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