beta-Glucuronidase/GUSB Products
Human beta-Glucuronidase (EC 3.2.1.31) encoded by the GUSB gene is a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans that include heparan sulfate, chondroitin sulfate and hyaluronan. The enzyme is only active on the glucuronic acid of the non-reducing end. The native protein has been reported as a tetrameric glycoprotein composed of identical subunits. Mutations in the GUSB gene are linked to mucopolysaccharidosis type VII. Accumulation of partially degraded glycosaminoglycans, with glucuronic acid residues at the non-reducing termini, are usually found in the lysosomes of patients with the disease. It has also been reported that this enzyme may contribute to the depletion of chondroitin from cartilage and thereby facilitate the damage of joints in rheumatoid arthritis.
46 results for "beta-Glucuronidase/GUSB" in Products
46 results for "beta-Glucuronidase/GUSB" in Products
beta-Glucuronidase/GUSB Products
Human beta-Glucuronidase (EC 3.2.1.31) encoded by the GUSB gene is a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans that include heparan sulfate, chondroitin sulfate and hyaluronan. The enzyme is only active on the glucuronic acid of the non-reducing end. The native protein has been reported as a tetrameric glycoprotein composed of identical subunits. Mutations in the GUSB gene are linked to mucopolysaccharidosis type VII. Accumulation of partially degraded glycosaminoglycans, with glucuronic acid residues at the non-reducing termini, are usually found in the lysosomes of patients with the disease. It has also been reported that this enzyme may contribute to the depletion of chondroitin from cartilage and thereby facilitate the damage of joints in rheumatoid arthritis.
| Source: | NS0 |
| Accession #: | AAA52561 |
| Applications: | EnzAct |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: beta-Glucuronidase/GUSB Antibody [NBP1-87511]](https://resources.bio-techne.com/images/products/beta-Glucuronidase-GUSB-Antibody-Immunohistochemistry-Paraffin-NBP1-87511-img0009.jpg "Immunohistochemistry-Paraffin: beta-Glucuronidase/GUSB Antibody [NBP1-87511]")
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: beta-Glucuronidase/GUSB Antibody [NBP2-38293]](https://resources.bio-techne.com/images/products/beta-Glucuronidase-GUSB-Antibody-Immunohistochemistry-Paraffin-NBP2-38293-img0003.jpg "Immunohistochemistry-Paraffin: beta-Glucuronidase/GUSB Antibody [NBP2-38293]")
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR2217 |
| Applications: | IHC, WB, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG Polyclonal |
| Applications: | WB |
![Western Blot: beta-Glucuronidase/GUSB Antibody [H00002990-B01P]](https://resources.bio-techne.com/images/products/beta-Glucuronidase-GUSB-Antibody-Western-Blot-H00002990-B01P-img0003.jpg "Western Blot: beta-Glucuronidase/GUSB Antibody [H00002990-B01P]")
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: beta-Glucuronidase/GUSB Antibody [H00002990-D01P]](https://resources.bio-techne.com/images/products/beta-Glucuronidase-GUSB-Antibody-Western-Blot-H00002990-D01P-img0001.jpg "Western Blot: beta-Glucuronidase/GUSB Antibody [H00002990-D01P]")
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #4U0E2 |
| Applications: | WB |
![Western Blot: beta-Glucuronidase/GUSB Antibody (4U0E2) [NBP3-15711]](https://resources.bio-techne.com/images/products/beta-Glucuronidase-GUSB-Antibody-4U0E2-Western-Blot-NBP3-15711-img0001.jpg "Western Blot: beta-Glucuronidase/GUSB Antibody (4U0E2) [NBP3-15711]")
| Applications: | WB |
![Western Blot: beta-Glucuronidase/GUSB Overexpression Lysate [NBL1-11412]](https://resources.bio-techne.com/images/products/beta-Glucuronidase-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11412-img0002.jpg "Western Blot: beta-Glucuronidase/GUSB Overexpression Lysate [NBL1-11412]")
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
![beta-Glucuronidase/GUSB Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/af6144cl1_sheep-beta-glucuronidase-gusb-pab-corafluor-1-89202516304612.png "Product Feature: CoraFluor Probes for TR-FRET")
| Applications: | AC |
| Applications: | ELISA |
| Applications: | ELISA |
