Bcl G Products
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bcl-G. The mRNA of Bcl-G encodes 2 isoforms, Bcl-GL, which is widely expressed in multiple tissues, and Bcl-GS, which is only found in testis. The Bcl-GS protein is predominantly localized to cytoplasmic organelles whereas Bcl-GL was distributed throughout the cytosol. Overexpression of either protein induced apoptosis, although Bcl-GS was far more potent than Bcl-GS. Apoptosis induction was dependent on the BH3 domain and could be suppressed by co-expression with the anti-apoptotic Bcl-XL protein.
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51 results for "Bcl G" in Products
51 results for "Bcl G" in Products
Bcl G Products
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bcl-G. The mRNA of Bcl-G encodes 2 isoforms, Bcl-GL, which is widely expressed in multiple tissues, and Bcl-GS, which is only found in testis. The Bcl-GS protein is predominantly localized to cytoplasmic organelles whereas Bcl-GL was distributed throughout the cytosol. Overexpression of either protein induced apoptosis, although Bcl-GS was far more potent than Bcl-GS. Apoptosis induction was dependent on the BH3 domain and could be suppressed by co-expression with the anti-apoptotic Bcl-XL protein.
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #6R9F3 |
| Applications: | IHC, WB |
![Western Blot: Bcl G Antibody (6R9F3) [NBP3-15746]](https://resources.bio-techne.com/images/products/Bcl-G-Antibody-6R9F3-Western-Blot-NBP3-15746-img0004.jpg "Western Blot: Bcl G Antibody (6R9F3) [NBP3-15746]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Bcl G Antibody [NBP1-91697]](https://resources.bio-techne.com/images/products/Bcl-G-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-91697-img0006.jpg "Immunocytochemistry/ Immunofluorescence: Bcl G Antibody [NBP1-91697]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S06-3D8 |
| Applications: | WB, ICC/IF |
![Western Blot: Bcl G Antibody (S06-3D8) [NBP3-19984]](https://resources.bio-techne.com/images/products/Bcl-G-Antibody-S06-3D8-Western-Blot-NBP3-19984-img0002.jpg "Western Blot: Bcl G Antibody (S06-3D8) [NBP3-19984]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1F2 |
| Applications: | WB, ELISA |
![Western Blot: Bcl G Antibody (1F2) [H00079370-M01]](https://resources.bio-techne.com/images/products/Bcl-G-Antibody-1F2-Western-Blot-H00079370-M01-img0004.jpg "Western Blot: Bcl G Antibody (1F2) [H00079370-M01]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI6D1 |
| Applications: | IHC, WB |
![Western Blot: Bcl G Antibody (OTI6D1)Azide and BSA Free [NBP2-72204]](https://resources.bio-techne.com/images/products/Bcl-G-Antibody-OTI6D1-Azide-and-BSA-Free-Western-Blot-NBP2-72204-img0001.jpg "Western Blot: Bcl G Antibody (OTI6D1)Azide and BSA Free [NBP2-72204]")
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| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1D11 |
| Applications: | WB, ELISA, IP |
![Western Blot: Bcl G Antibody (1D11) [H00079370-M02]](https://resources.bio-techne.com/images/products/Bcl-G-Antibody-1D11-Western-Blot-H00079370-M02-img0003.jpg "Western Blot: Bcl G Antibody (1D11) [H00079370-M02]")
![Western Blot: Bcl G Overexpression Lysate [NBL1-07949]](https://resources.bio-techne.com/images/products/Bcl-G-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-07949-img0002.jpg "Western Blot: Bcl G Overexpression Lysate [NBL1-07949]")
![Western Blot: Bcl G Overexpression Lysate [NBP2-05635]](https://resources.bio-techne.com/images/products/Bcl-G-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-05635-img0001.jpg "Western Blot: Bcl G Overexpression Lysate [NBP2-05635]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI6D1 |
| Applications: | IHC, WB |
![Western Blot: Bcl G Antibody (OTI6D1) [NBP2-46570]](https://resources.bio-techne.com/images/products/Bcl-G-Antibody-OTI6D1-Western-Blot-NBP2-46570-img0001.jpg "Western Blot: Bcl G Antibody (OTI6D1) [NBP2-46570]")
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| Reactivity: | Hamster |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
Bcl G Antibody (24GB3005)
Catalog #:
NBP3-50681
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #24GB3005 |
| Applications: | WB, ICC/IF, Flow |
![Western Blot: Bcl G Overexpression Lysate [NBP2-05634]](https://resources.bio-techne.com/images/products/Bcl-G-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-05634-img0001.jpg "Western Blot: Bcl G Overexpression Lysate [NBP2-05634]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI6D1 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI6D1 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI6D1 |
| Applications: | IHC, WB |
![Bcl G Antibody (OTI6D1) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp2-72204cl1_mouse-bcl-g-mab-oti6d1-corafluor-1-25920251283316.png "Product Feature: CoraFluor Probes for TR-FRET")
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI6D1 |
| Applications: | IHC, WB |
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI6D1 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI6D1 |
| Applications: | IHC, WB |
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI6D1 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI6D1 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI6D1 |
| Applications: | IHC |
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