291 results for "ATM" in Products
ATM Products
Germline mutations in the Ataxia Telangiectasia-mutated (ATM) gene lead to the multi-symptom disorder A-T (Ataxia Telangiectasia). Immunodeficiency, neurodegeneration, premature aging, sensitivity to ionizing radiation, and a predisposition to certain types of cancer characterize A-T. The protein product of the gene mutated in A-T is a large protein kinase involved in cell cycle checkpoint and genotoxic stress responses. The ATM protein kinase exists as a dimer in the cell nucleus. Changes in DNA structure induced by genotoxic stress lead to activation of ATM and phosphorylation of S1981 in trans. Once S1981 is phosphorylated, the dimer dissociates and active ATM monomers signal to downstream targets.
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #664703 |
| Applications: | ICC |
| Reactivity: | Human, Mouse, Rat, Monkey, Hamster - Cricetulus (Chinese Hamster) |
| Details: | Mouse IgG1 Monoclonal Clone #2C1 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +5 More |
![Western Blot: ATM Antibody (2C1) [NB100-309]](https://resources.bio-techne.com/images/products/ATM-Antibody-2C1-Western-Blot-NB100-309-img0018.jpg "Western Blot: ATM Antibody (2C1) [NB100-309]")
| Reactivity: | Human, Mouse, Rat, Canine, Kangaroo |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +3 More |
![Western Blot: ATM Antibody [NB100-104]](https://resources.bio-techne.com/images/products/ATM-Antibody-Western-Blot-NB100-104-img0009.jpg "Western Blot: ATM Antibody [NB100-104]")
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1163B |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1163B |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #664703 |
| Applications: | ICC |
Human/Mouse/Rat Phospho-ATM (S1981) Alexa Fluor™ Plus 680-conjugated Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
Human/Mouse/Rat Phospho-ATM (S1981) Alexa Fluor™ Plus 555-conjugated Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #664703 |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Reactivity: | Human, Mouse, Rat, Canine (Negative) |
| Details: | Mouse IgG1 kappa Monoclonal Clone #10H11.E12 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #3G11 |
| Applications: | IHC, ELISA, Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1163B |
Human/Mouse/Rat Phospho-ATM (S1981) Alexa Fluor™ Plus 405-conjugated Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
Human/Mouse/Rat Phospho-ATM (S1981) Alexa Fluor™ Plus 488-conjugated Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
Human/Mouse/Rat Phospho-ATM (S1981) Alexa Fluor™ Plus 647-conjugated Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
Human/Mouse/Rat Phospho-ATM (S1981) Alexa Fluor™ Plus 594-conjugated Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1163B |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |