AMBRA1 Products
AMBRA1 regulates autophagy and development of the nervous system. It is a large, previously unknown protein bearing a WD40 domain at its amino terminus, regulates autophagy and has a crucial role in embryogenesis. AMBRA1 is a positive regulator of the Becn1-dependent programme of autophagy, as revealed by its overexpression and by RNA interference experiments invitro. Notably, AMBRA1 functional deficiency in mouse embryos leads to severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic cell death.
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37 results for "AMBRA1" in Products
37 results for "AMBRA1" in Products
AMBRA1 Products
AMBRA1 regulates autophagy and development of the nervous system. It is a large, previously unknown protein bearing a WD40 domain at its amino terminus, regulates autophagy and has a crucial role in embryogenesis. AMBRA1 is a positive regulator of the Becn1-dependent programme of autophagy, as revealed by its overexpression and by RNA interference experiments invitro. Notably, AMBRA1 functional deficiency in mouse embryos leads to severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic cell death.
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: AMBRA1 Antibody - BSA Free [NBP1-07124]](https://resources.bio-techne.com/images/products/AMBRA1-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-07124-img0009.jpg "Immunocytochemistry/ Immunofluorescence: AMBRA1 Antibody - BSA Free [NBP1-07124]")
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| Reactivity: | Human, Mouse, Rat, Bovine, Chicken |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: AMBRA1 Antibody [NBP2-24723]](https://resources.bio-techne.com/images/products/AMBRA1-Antibody-Western-Blot-NBP2-24723-img0001.jpg "Western Blot: AMBRA1 Antibody [NBP2-24723]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: AMBRA1 Antibody [NBP1-30460]](https://resources.bio-techne.com/images/products/AMBRA1-Antibody-Western-Blot-NBP1-30460-img0002.jpg "Western Blot: AMBRA1 Antibody [NBP1-30460]")
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: AMBRA1 AntibodyBSA Free [NBP2-92081]](https://resources.bio-techne.com/images/products/AMBRA1-Antibody-Western-Blot-NBP2-92081-img0001.jpg "Western Blot: AMBRA1 AntibodyBSA Free [NBP2-92081]")
![Western Blot: AMBRA1 Overexpression Lysate [NBP2-06932]](https://resources.bio-techne.com/images/products/AMBRA1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-06932-img0001.jpg "Western Blot: AMBRA1 Overexpression Lysate [NBP2-06932]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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