Skip to main content

alpha-2B Adrenergic R/ADRA2B Products

Alpha-2-adrenergic receptors, including ADRA2B, are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C that have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. ADRA2B was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of ADRA2B was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization; this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity.

30 results for "alpha-2B Adrenergic R/ADRA2B" in Products

alpha-2B Adrenergic R/ADRA2B Products

Alpha-2-adrenergic receptors, including ADRA2B, are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C that have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. ADRA2B was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of ADRA2B was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization; this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity.

30 results for "alpha-2B Adrenergic R/ADRA2B" in Products

Selective α2 antagonist

α2 agonist

Selective α2 antagonist

Highly selective α2B antagonist

I1 ligand. Also α2 agonist

Potent and non-selective β antagonist; also potent α1 antagonist

Potent and selective α2 antagonist

Catalog #: FAB10324G
Flow

Potent, selective α2D antagonist

Potent, highly selective α2 agonist. Active isomer of medetomidine (Cat. No. 5160)

Selective α2 agonist

α2 agonist. Water-soluble form of UK 14,304 (Cat. No. 0425)

Potent and highly selective α2 agonist

Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

α2 agonist

Potent and selective α2 antagonist

Catalog #: FAB10324R
Flow
Flow, CyTOF-ready
Catalog #: FAB10324T
Flow
Catalog #: FAB10324V
Flow
Catalog #: FAB10324U
Flow
Catalog #: FAB10324S
Flow

α2B antagonist

α2 agonist. Also I2 selective ligand

D2-like agonist (D2>D3>D4)

Results Per Page
5 10 25 50
/ 2