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2 results for "Aldehyde Dehydrogenase 1-A1/ALDH1A1 Small Molecules and Peptides" in Products

Aldehyde Dehydrogenase 1-A1/ALDH1A1: Small Molecules and Peptides

Aldehyde dehydrogenases (ALDHs) are NAD(P)+-dependent enzymes that detoxify aldehydes by oxidizing them to carboxylic acids. Nineteen ALDHs are present in humans, expressed in a variety of organelles and having different substrate preferences. ALDH1A1 is a cytosolic enzyme that preferentially oxidizes retinaldehyde to retinoic acid. ALDH1A1 is expressed in the epithelium of many organs, including brain, liver, testis, eye lens and cornea. ALDH1A1 is highly expressed in brain dopaminergic ...

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Potent and selective ALDH1A1 inhibitor

ALDH1A1 inhibitor

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