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3 results for "Agrin" in Products

Agrin Products

Agrin is a 400-600 kDa heparan sulfate proteoglycan component of the extracellular matrix. Multiple forms of are generated by alternative splicing and proteolytic cleavage. Agrin binds to BMP-2, BMP-4, and TGF-beta, and it blocks BMP-induced signaling through BMPR-IA. Agrin binds to a complex of alpha-Dystroglycan, MuSK, and LRP4 on myotubes and induces the clustering of AChR and motoneuron-myotube adhesion at the neuromuscular junction. It binds the Abeta (1-40) peptide in Alzheimer’s ...

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Reactivity:
Rat
Details:
Goat IgG Polyclonal
Applications:
WB, ELISA(Det)
Reactivity:
Mouse, Rat
Details:
Mouse IgG2 Alpha Monoclonal Clone #AGR 131
Applications:
IHC, WB, ICC/IF, Endotoxin
Novus Antibodies
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