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New Immunology Activity Book

This fun activity book includes immunology-themed crossword puzzles, word finds, mazes, and coloring pages. Take time out from your hectic research schedule to sit back, relax, and put your immunology puzzle-solving skills to work.

Cell Markers Guide for Human Immune Cell Characterization by Flow Cytometry 

Identifying different immune cell types can be difficult if you don’t know which markers to use. Our new guide for human immune cell characterization can help. This quick reference tool shows the markers commonly used to distinguish specific immune cell types by flow cytometry.

Immune Cell Isolation & Culture Guide

From natural killer cells and macrophages to dendritic cells and T cells, Bio-Techne offers cell selection and differentiation kits, cell culture media, fetal bovine serum, and an unparalleled selection of recombinant proteins and antibodies. Additionally, we continue to expand our selection of innovative tools for ex vivo cell manufacturing, making it easier for scientists to transition their research from discovery to the clinic. Learn more in this guide that describes the tools that we offer for isolating and culturing different immune cell types.

Cell Markers Interactive Resource Tool

Cell surface and intracellular markers are frequently utilized to identify different immune cell types. Explore our new Cell Markers Interactive Resource Tool to find the human and mouse markers that are most commonly used in the scientific literature to distinguish different immune cell types or cell-type-specific subsets.

Flow Cytometry eHandbook

Flow cytometry is a powerful technique that is widely used to identify and characterize different immune cell types in heterogeneous samples. For a clear, easy-to-follow guide to designing flow cytometry experiments and data analysis, explore our Flow Cytometry Handbook.

Current and Emerging Immune Checkpoint Targets eBook

Immune checkpoint proteins play a central role in regulating the activities of different immune cell types and represent some of the most promising targets for cancer immunotherapy. This eBook highlights some of the immune checkpoint molecules that are being investigated as immuno-oncology targets, and the products that we offer for studying these molecules.

New! Immune Checkpoint Targets Wall Poster

Immune checkpoint molecules deliver signals that control the activities of different immune cell types and represent some of the most highly investigated targets for immuno-oncology research. Use our new wall poster to explore the current and emerging immune checkpoint molecules being investigated as potential cancer immunotherapy targets.

Full Signaling Pathway Analysis in a Single Run with Simple Western™ Tech Note

Due to the complexity of signaling networks, a high-throughput method is often needed to measure all of the proteins involved. Download this Tech Note to learn how Simple Western’s high-throughput and low sample volume requirements work together to comprehensively characterize complex signaling pathways overnight.

A Look Inside a Tumor: Mechanisms of Tumor Evasion and Immunosuppression in the Tumor Microenvironment

The tumor microenvironment (TME) plays a central role in inhibiting anti-tumor immune responses. Use our new poster to learn about the key mechanisms by which tumor cells, tumor-derived exosomes, regulatory T cells, myeloid-derived suppressor cells (MDSCs), and tumor-associated macrophages (TAMs) mediate immunosuppression in the TME.

Scientific Poster: Evaluation of the Expression of Immune Functional Markers in the Tumor Microenvironment

RNAscope® is an advanced in situ hybridization assay that allows for the visualization of single cell gene expression, targeting mRNA sequences directly in tissues. Learn more in this scientific poster showing how the technique can be utilized to evaluate the expression profiles of immune checkpoint and immune functional markers in the tumor microenvironment and the insight that this data may provide into potential combination therapies targeting different checkpoint pathways.

Evalulating CAR Expression on CAR-T Cells Using Fluorokines™

One of the current challenges in the field of CAR-T cell therapy is the lack of a simple assay to easily detect and quantify CAR expression following T cell transduction. Read this application note to learn about the advantages of using R&D Systems™ Fluorokines fluorescent-labeled proteins to directly stain and detect CAR+ cells by flow cytometry.

T Cell-Based Therapies eBook

This new eBook provides an overview of several biological and manufacturing challenges facing the development and production of T cell therapies. It follows with examples of how Bio-Techne products and services can address these challenges at each stage of the process.