Idazoxan hydrochloride

Name: Idazoxan hydrochloride
Brand: Tocris Bioscience
SKU: 0793

Tocris Bioscience, part of Bio-Techne | Catalog # 0793

Citations (2)

COA / SDS

α2 antagonist. Also I2 ligand

Discontinued Product

0793 has been discontinued. View all Adrenergic alpha-2 Receptor Antagonists products.

Key Product Details

Description:	α₂ antagonist. Also I₂ ligand
Alternative Names:	RX 781094
Chemical Name:	2-(1,4-Benzodioxan-2-yl)-2-imidazoline hydrochloride
Purity:	≥98%
Molecular Weight:	240.69

View Full Technical Details for Idazoxan hydrochloride

Technical Data
Citations

Biological Activity for Idazoxan hydrochloride

Idazoxan hydrochloride is a α₂-adrenoceptor antagonist, and I₂ ligand, selective over I₁ sites (pK_i values are 5.90, 7.22, 8.01, 7.43, and 7.7 for I₁, I₂, α_2A, α_2B, and α_2C receptors respectively).

Technical Data for Idazoxan hydrochloride

M. Wt	240.69
Formula	C₁₁H₁₂N₂O₂.HCl
Storage	Store at RT
Purity	≥98%
CAS Number	79944-56-2
PubChem ID	154494
InChi Key	MYUBYOVCLMEAOH-UHFFFAOYSA-N
Smiles	Cl.C1CN=C(N1)C1COC2=CC=CC=C2O1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Idazoxan hydrochloride

References are publications that support the biological activity of the product.

Michel and Ernsberger Keeping an eye on the I site: imidazoline-preferring receptors. TIPS 1992 PMID: 1413085
Dabir Idazoxan: a novel pharmacological tool for the study of α₂-adrenoceptors. J.Pharmacol. 1986 PMID: 2875218
Eglen 'Seeing through a glass darkly': casting light on imidazoline 'I' sites. TiPS 1998 PMID: 9786027
Berdeu Evidence for two different imidazoline sites on pancreatic B cells and vascular bed in rat. Eur.J.Pharmacol. 1995 PMID: 7774667

Idazoxan hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0793

Key Product Details

Biological Activity for Idazoxan hydrochloride

Technical Data for Idazoxan hydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Idazoxan hydrochloride

Product Documents for Idazoxan hydrochloride

COA

Certificate of Analysis

SDS

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