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CD45RC Antibody (C455.1F) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28135

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry, Immunoprecipitation

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Monoclonal Rat IgG2a Kappa Clone # C455.1F

Concentration

0.1 mg/ml

Product Specifications

Immunogen

An exon C-dependent epitope of CD45 glycoprotein

Reactivity Notes

Mouse.

Specificity

An exon C-dependent epitope of CD45 glycoprotein

Clonality

Monoclonal

Host

Rat

Isotype

IgG2a Kappa

Scientific Data Images for CD45RC Antibody (C455.1F) [PE]

Flow Cytometry: CD45RC Antibody (C455.1F) [PE] [NBP1-28135] - Cells from BALB/c spleen were double stained with rat anti-CD45RC-R-PE and rat anti-mouse CD8a-FITC (Clone 53-6.7), following which small lymphocytes were gated and analyzed on a Flow cytometer

Applications for CD45RC Antibody (C455.1F) [PE]

Application
Recommended Usage

Flow Cytometry

0.2 ug/10^6 cells

Immunoprecipitation

1:10-1:500

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS and a stabilizing agent

Preservative

Sodium Azide

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CD45RC

The CD45 family of cell-surface glycoprotein antigens exist as a set of isoforms. (1-4) The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T-200 species. (1-4) The 'restricted' subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. (1)

Alternate Names

B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Gene Symbol

PTPRC

Additional CD45RC Products

Product Documents for CD45RC Antibody (C455.1F) [PE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD45RC Antibody (C455.1F) [PE]

Protect conjugated forms from light.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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