d[Cha4]-AVP
Tocris Bioscience, part of Bio-Techne | Catalog # 3126
Potent and selective human V1B agonist
Discontinued Product
3126 has been discontinued.
View all Vasopressin Receptor Agonists products.
Key Product Details
Description
Potent and selective human V1B agonist
Product Description
d[Cha4]-AVP is a potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secretion and exhibits negligible vasopressor activity in vivo.Product Specifications
Molecular Weight
1094.31
Formula
C50H71N13O11S2
Storage
Store at -20°C
CAS Number
500170-27-4
PubChem ID
44419028
InChI Key
ZKYCVZNKBXGNEK-ZTYVOHGWSA-N
SMILES
NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSCCC(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CC2CCCCC2)C(=O)N[C@@H](CC(N)=O)C(=O)N1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Cheng Design of potent and selective agonists for the human vasopressin V1b receptor based on modifications of [deamino-cys1]arginine vasopressin at position 4. J.Med.Chem. 2004 PMID: 15084136
- Pena Design and synthesis of the frist selective agonists for the rat vasopressin V1b receptor: based on modifications of deamino-[cys1]arginine vasopressin at positions 4 and 8. J.Med.Chem. 2007 PMID: 17300166
- Derick [1-Deamino-4-cyclohexylalanine] arginine vasopressin: a potent and specific agonist for vasopressin V1b receptors. Endocrinology 2002 PMID: 12446593
Product Specific Notices for d[Cha4]-AVP
For research use only
Loading...
Loading...