S-Isopropylisothiourea hydrobromide

Name: S -Isopropylisothiourea hydrobromide
Brand: Tocris Bioscience
SKU: 0897

Tocris Bioscience, part of Bio-Techne | Catalog # 0897

COA / SDS

iNOS inhibitor, acts at arginine binding site

Discontinued Product

0897 has been discontinued. View all iNOS Inhibitors products.

Key Product Details

Description:	iNOS inhibitor, acts at arginine binding site
Molecular Weight:	199.11

View Full Technical Details for S-Isopropylisothiourea hydrobromide

Technical Data
Citations

Biological Activity for S-Isopropylisothiourea hydrobromide

S-Isopropylisothiourea hydrobromide is a potent inhibitor of NO synthase, with selectivity for the inducible form.

Technical Data for S-Isopropylisothiourea hydrobromide

M. Wt	199.11
Formula	C₄H₁₀N₂S.HBr
Storage	Store at RT
CAS Number	4269-97-0
PubChem ID	9813062
InChi Key	SLGVZEOMLCTKRK-UHFFFAOYSA-N
Smiles	Br.CC(C)SC(=N)N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for S-Isopropylisothiourea hydrobromide

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	19.91	100

Preparing Stock Solutions for S-Isopropylisothiourea hydrobromide

The following data is based on the product molecular weight 199.11.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.02 mL	25.11 mL	50.22 mL
5 mM	1.00 mL	5.02 mL	10.04 mL
10 mM	0.50 mL	2.51 mL	5.02 mL
50 mM	0.10 mL	0.50 mL	1.00 mL

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Reconstitution Calculator

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References for S-Isopropylisothiourea hydrobromide

References are publications that support the biological activity of the product.

Moore and Handy Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 1997 PMID: 9226999
Handy Effect of S-methylisothiourea on neuronal nitric oxide synthase, nociception and blood pressure in the mouse. Br.J.Pharmacol.
Garvey Potent and selective inhibition of human nitric oxide synthases. J.Biol.Chem. 1994 PMID: 7523409