c-Di-AMP sodium salt

Tocris Bioscience, part of Bio-Techne | Catalog # 5901

Endogenous STING and DDX41 agonist; activates STING-dependent signaling
Discontinued Product
5901 has been discontinued. View all STING-dependent Signaling Antagonists products.

Key Product Details

Description

Endogenous STING and DDX41 agonist; activates STING-dependent signaling

View all STING-dependent Signaling Antagonists »

Product Description

c-Di-AMP sodium salt is an endogenous STING and DDX41 agonist; mediates DDX41-STING interaction. Activates STING-dependent IFN-β production in mouse and human cells. Also A2A inverse agonist. Selectively induces apoptosis of monocytes in human PBMC cultures and in NSG mice transplanted with human CD34+ cells.

This product is sold in units of 702μg, equivalent to 1μmol.

Product Specifications

Molecular Weight

702.38

Formula

C20H22N10Na2O12P2

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

3',5'-Cyclic diadenylic acid sodium salt

CAS Number

2734909-87-4

PubChem ID

11158091

InChI Key

PDXMFTWFFKBFIN-XPWFQUROSA-N

SMILES

O=P(O[C@H]1[C@H]([C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1CO4)O)(O[Na])OC[C@@H]5[C@H]([C@H]([C@H](N6C=NC7=C6N=CN=C7N)O5)O)OP4(O[Na])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 14.05 20

Preparing Stock Solutions for c-Di-AMP sodium salt

The following data is based on the product molecular weight 702.38

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 7.12 mL 35.59 mL 71.19 mL
1 mM 1.42 mL 7.12 mL 14.24 mL
2 mM 0.71 mL 3.56 mL 7.12 mL
10 mM 0.14 mL 0.71 mL 1.42 mL

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Product Documents for c-Di-AMP sodium salt

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for c-Di-AMP sodium salt

For research use only

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