DLPC

Name: DLPC
Brand: Tocris Bioscience
SKU: 4378

Tocris Bioscience, part of Bio-Techne | Catalog # 4378

Citations (2)

COA / SDS

LRH-1 agonist; regulates bile acid metabolism

Discontinued Product

4378 has been discontinued. View all Nuclear Receptor Agonists products.

Key Product Details

Description:	LRH-1 agonist; regulates bile acid metabolism
Chemical Name:	(7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxododecyl)oxy]-3,5,9-trioxa-4-phosphaheneicosan-1-aminium-4-oxide
Molecular Weight:	621.83

View Full Technical Details for DLPC

Technical Data
Citations

Biological Activity for DLPC

Selective agonist of the orphan nuclear receptor LRH-1 (liver receptor homolog-1, NR5A2) in vitro. Induces bile acid biosynthetic enzymes; increases bile acid and decreases hepatic triglycerides and serum glucose. Exhibits antidiabetic effects.

Technical Data for DLPC

M. Wt	621.83
Formula	C₃₂H₆₄NO₈P
Storage	Store at -20°C
CAS Number	18194-25-7
PubChem ID	512874
InChi Key	IJFVSSZAOYLHEE-SSEXGKCCSA-N
Smiles	[O-]P(OC[C@H](OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)(OCC[N+](C)(C)C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for DLPC

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	ethanol	62.18	100

Preparing Stock Solutions for DLPC

The following data is based on the product molecular weight 621.83.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.61 mL	8.04 mL	16.08 mL
5 mM	0.32 mL	1.61 mL	3.22 mL
10 mM	0.16 mL	0.80 mL	1.61 mL
50 mM	0.03 mL	0.16 mL	0.32 mL

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References for DLPC

References are publications that support the biological activity of the product.

Lee A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. Nature 2011 PMID: 21614002