UF 010

Tocris Bioscience, part of Bio-Techne | Catalog # 5588

Class I HDAC inhibitor
Discontinued Product
5588 has been discontinued. View all Class I Histone Deacetylases Inhibitors products.

Key Product Details

Description

Class I HDAC inhibitor

View all Class I Histone Deacetylases Inhibitors »

Product Description

Class I HDAC inhibitor (IC50 values are 0.06, 0.1, 0.5 and 1.5 μM for HDACs 3, 2, 1 and 8, respectively). Exhibits >6-fold selectivity over other HDACs. Induces accumulation of acetylated histones in HCT116 cells in vitro. Inhibits proliferation of a range of cancer cell lines. Arrests cells at G1/S transition.

Product Specifications

Molecular Weight

271.15

Formula

C11H15BrN2O

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

4-Bromo-N'-butylbenzohydrazide

CAS Number

537672-41-6

PubChem ID

4596836

InChI Key

BVQCFCYPFJOOAV-UHFFFAOYSA-N

SMILES

BrC1=CC=C(C(NNCCCC)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 27.11 100
Ethanol 27.11 100

Preparing Stock Solutions for UF 010

The following data is based on the product molecular weight 271.15

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.69 mL 18.44 mL 36.88 mL
5 mM 0.74 mL 3.69 mL 7.38 mL
10 mM 0.37 mL 1.84 mL 3.69 mL
50 mM 0.07 mL 0.37 mL 0.74 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for UF 010

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for UF 010

For research use only

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