W-5 hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0368
Calmodulin antagonist
Discontinued Product
0368 has been discontinued.
View all Calcium Binding Protein Modulator Antagonists products.
Key Product Details
Description
Calmodulin antagonist
Product Description
W-5 hydrochloride is a calmodulin antagonist (inhibits Ca2+-calmodulin dependent PDE with an IC50 of 240 μM).Product Specifications
Molecular Weight
342.88
Formula
C16H22N2O2S.HCl
Storage
Store at RT
Chemical Name
N-(6-Aminohexyl)-1-naphthalenesulfonamide hydrochloride
CAS Number
61714-25-8
PubChem ID
173829
InChI Key
HOCSVIGHWPLMFC-UHFFFAOYSA-N
SMILES
Cl.NCCCCCCNS(=O)(=O)C1=C2C=CC=CC2=CC=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 3.43 | 10 | |
| DMSO | 17.14 | 50 |
Preparing Stock Solutions
for W-5 hydrochloride
The following data is based on the product molecular weight 342.88
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 5.83 mL | 29.16 mL | 58.33 mL |
| 2.5 mM | 1.17 mL | 5.83 mL | 11.67 mL |
| 5 mM | 0.58 mL | 2.92 mL | 5.83 mL |
| 25 mM | 0.12 mL | 0.58 mL | 1.17 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Hidaka N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc.Natl.Acad.Sci.U.S.A. 1981 PMID: 6945588
- Hidaka and Tanaka Naphthalenesulfonamides as calmodulin antagonists. Methods Enzymol. 1983 PMID: 6139736
- Hidaka Activity-structure relationship of calmodulin antagonists. Naphthalenesulfonamide derivatives. Mol.Pharmacol. 1981 PMID: 7329399
Product Specific Notices for W-5 hydrochloride
For research use only
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