VUF 5574

Tocris Bioscience, part of Bio-Techne | Catalog # 1359

Potent, selective hA3 antagonist
Discontinued Product
1359 has been discontinued. View all Adenosine A3 Receptor Antagonists products.

Key Product Details

Description

Potent, selective hA3 antagonist

View all Adenosine A3 Receptor Antagonists »

Product Description

VUF 5574 is a potent, selective, competitive antagonist for the human adenosine A3 receptor (Ki = 4 nM). Displays ≥ 2500-fold selectivity over A1 and A2A receptors.

Product Specifications

Molecular Weight

371.39

Formula

C21H17N5O2

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

N-(2-Methoxyphenyl)-N'-[2-(3-pyrindinyl)-4-quinazolinyl]-urea

CAS Number

280570-45-8

PubChem ID

4046493

InChI Key

YRAFEJSZTVWUMD-UHFFFAOYSA-N

SMILES

O=C(NC2=NC(C4=CC=CN=C4)=NC3=C2C=CC=C3)NC1=C(OC)C=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 1.49 4

Preparing Stock Solutions for VUF 5574

The following data is based on the product molecular weight 371.39

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.04 mM 67.31 mL 336.57 mL 673.15 mL
0.2 mM 13.46 mL 67.31 mL 134.63 mL
0.4 mM 6.73 mL 33.66 mL 67.31 mL
2 mM 1.35 mL 6.73 mL 13.46 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for VUF 5574

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for VUF 5574

For research use only

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