VUF 11207 fumarate

Name: VUF 11207 fumarate
Brand: Tocris Bioscience
SKU: 4780

Tocris Bioscience, part of Bio-Techne | Catalog # 4780

COA / SDS

Potent ACKR3 (CXCR7) agonist

Discontinued Product

4780 has been discontinued. View all Chemokine Receptor Agonists products.

Key Product Details

Description:	Potent ACKR3 (CXCR7) agonist
Chemical Name:	N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzamide fumarate
Purity:	≥98% (HPLC)
Molecular Weight:	586.65

View Full Technical Details for VUF 11207 fumarate

Technical Data
Citations

Biological Activity for VUF 11207 fumarate

VUF 11207 fumarate is a potent ACKR3 (CXCR7) chemokine receptor agonist (EC₅₀ = 1.6 nM). Induces recruitment of β-arrestin to CXCR7 in HEK293-CXCR7 cells.

Compound Libraries for VUF 11207 fumarate

VUF 11207 fumarate is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for VUF 11207 fumarate

M. Wt	586.65
Formula	C₂₇H₃₅FN₂O₄.C₄H₄O₄
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1785665-61-3
PubChem ID	90488970
InChi Key	MTPOECCHJLVVGO-FDULSSLPSA-N
Smiles	C\C(CN(CCC2N(C)CCC2)C(C3=CC(OC)=C(OC)C(OC)=C3)=O)=C/C1=C(F)C=CC=C1.OC(/C=C/C(O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for VUF 11207 fumarate

References are publications that support the biological activity of the product.

Wijtmans Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists. Eur.J.Med.Chem. 2012 PMID: 22424612