VUF 11207 fumarate
Tocris Bioscience, part of Bio-Techne | Catalog # 4780
Potent ACKR3 (CXCR7) agonist
Discontinued Product
4780 has been discontinued.
View all Chemokine Receptor Agonists products.
Product Description
VUF 11207 fumarate is a potent ACKR3 (CXCR7) chemokine receptor agonist (EC50 = 1.6 nM). Induces recruitment of β-arrestin to CXCR7 in HEK293-CXCR7 cells.Product Specifications
Molecular Weight
586.65
Formula
C27H35FN2O4.C4H4O4
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzamide fumarate
CAS Number
1785665-61-3
PubChem ID
90488970
InChI Key
MTPOECCHJLVVGO-FDULSSLPSA-N
SMILES
C\C(CN(CCC2N(C)CCC2)C(C3=CC(OC)=C(OC)C(OC)=C3)=O)=C/C1=C(F)C=CC=C1.OC(/C=C/C(O)=O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 58.66 | 100 | |
| DMSO | 58.66 | 100 |
Preparing Stock Solutions
for VUF 11207 fumarate
The following data is based on the product molecular weight 586.65
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.70 mL | 8.52 mL | 17.05 mL |
| 5 mM | 0.34 mL | 1.70 mL | 3.41 mL |
| 10 mM | 0.17 mL | 0.85 mL | 1.70 mL |
| 50 mM | 0.03 mL | 0.17 mL | 0.34 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Wijtmans Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists. Eur.J.Med.Chem. 2012 PMID: 22424612
Product Specific Notices for VUF 11207 fumarate
For research use only
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