VU 0365114

Tocris Bioscience, part of Bio-Techne | Catalog # 4404

Positive allosteric modulator of M5 receptors
Discontinued Product
4404 has been discontinued. View all mAChR M5 Modulators products.

Key Product Details

Description

Positive allosteric modulator of M5 receptors

View all mAChR M5 Modulators »

Product Description

VU 0365114 is a selective positive allosteric modulator of M5 (EC50 values are 2.7 μM for human M5, and >30 μM for M1, M2, M3 and M4 receptors).

Product Specifications

Molecular Weight

397.35

Formula

C22H14F3NO3

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

1-[(1,1'-Biphenyl)-4-ylmethyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione

CAS Number

1208222-39-2

PubChem ID

45281794

InChI Key

SPBGRXOPAXZSER-UHFFFAOYSA-N

SMILES

O=C(C1=CC(OC(F)(F)F)=CC=C1N2CC3=CC=C(C4=CC=CC=C4)C=C3)C2=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.73 100
Ethanol 3.97 10

Preparing Stock Solutions for VU 0365114

The following data is based on the product molecular weight 397.35

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.52 mL 12.58 mL 25.17 mL
5 mM 0.50 mL 2.52 mL 5.03 mL
10 mM 0.25 mL 1.26 mL 2.52 mL
50 mM 0.05 mL 0.25 mL 0.50 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for VU 0365114

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for VU 0365114

For research use only

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