Vinpocetine

Name: Vinpocetine
Brand: Tocris Bioscience
SKU: 0757

Tocris Bioscience a Bio-Techne Brand

Catalog # 0757

Citations (2)

COA / SDS

Discontinued Product

0757 has been discontinued. View all Voltage-gated Sodium Channel Blockers products.

Key Product Details

Description:	Na⁺ channel blocker
Chemical Name:	(3α,16α)-Eburnamenine-14-carboxylic acid ethyl ester
Purity:	≥99% (HPLC)
Molecular Weight:	350.46

View Full Technical Details for Vinpocetine

Biological Activity for Vinpocetine

Vinpocetine is a phosphodiesterase inhibitor, selective for PDE1 (IC₅₀ = 21 μM). Also blocks voltage-gated Na⁺ channels.

Technical Data for Vinpocetine

M. Wt	350.46
Formula	C₂₂H₂₆N₂O₂
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	42971-09-5
PubChem ID	443955
InChi Key	DDNCQMVWWZOMLN-IRLDBZIGSA-N
Smiles	O=C(OCC)C5=C[C@@]2(CC)[C@@]1([H])C4=C(C3=CC=CC=C3N45)CCN1CCC2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Vinpocetine

References are publications that support the biological activity of the product.

Molnar and Erdo Vinpocetine is as potent as phen. to block voltage-gated Na⁺ channels in rat cortical neurons. Eur.J.Pharmacol. 1995 PMID: 7737339
Hagiwara Effect of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle. Biochem.Pharmacol. 1984 PMID: 6322804

Citations for Vinpocetine (2)

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Citations are publications that use Bio-Techne products. Selected citations for Vinpocetine include:

Lee et al. (2015) Vinpocetine inhibits Streptococcus pneumoniae-induced upregulation of mucin MUC5AC expression via induction of MKP-1 phosphatase in the pathogenesis of otitis media. EMBO Mol Med. 194:5990
PMID: 25972475
Robichaud et al. (2002) Assessing the emetic potential of PDE4 inhibitors in rats. Br J Pharmacol. 135:113
PMID: 11786486

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Product Documents for Vinpocetine

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.