VH 032 amide-PEG3-acid
Tocris Bioscience, part of Bio-Techne | Catalog # 6679
VHL ligand with PEG linker and terminal acid for onward chemistry
Discontinued Product
6679 has been discontinued.
View all VHL Ligands Plus Linker Building Blocks products.
Key Product Details
Description
VHL ligand with PEG linker and terminal acid for onward chemistry
Alternative Names
(S,R,S)-AHPC-PEG3-COOH
Product Description
VH 032 amide-PEG3-acid is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.This product has been recently renamed. The previous name for this product was VH 032 - linker 4
Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Usage Guidelines
This product is provided for use in onward chemistry. Suitable solvents can be used.Product Specifications
Molecular Weight
662.79
Formula
C32H46N4O9S
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(S)-15-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-16,16-dimethyl-13-oxo-4,7,10-trioxa-14-azaheptadecanoic acid
CAS Number
2140807-42-5
PubChem ID
132020301
InChI Key
YHEJFYORSLEJKX-BEYSDYMESA-N
SMILES
CC1=C(C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(C)C)NC(CCOCCOCCOCCC(O)=O)=O)=O)O)=O)SC=N1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
Molarity Calculator
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Product Specific Notices for VH 032 amide-PEG3-acid
For research use only
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